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    Association details:
    Biomarker:IGFBP7 overexpression
    Cancer:Estrogen Receptor Positive Breast Cancer
    Drug:tamoxifen (Estrogen receptor antagonist)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: B - Late Trials
    Source:
    Carcinogenesis
    Title:

    Prognostic impact of tumor-specific insulin-like growth factor binding protein 7 (IGFBP7) levels in breast cancer: A prospective cohort study

    Published date:
    10/04/2021
    Excerpt:
    ...the combination of IGFBP7high and estrogen receptor-positive tumors was associated with low recurrence risk only in tamoxifen-treated patients (Pinteraction= 0.029)....IGFBP7 merits further investigation to confirm whether it could be a suitable biomarker for treatment selection.
    DOI:
    10.1093/carcin/bgab090