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Association details:
Biomarker:IGF2R overexpression
Cancer:Gastric Cancer
Regimen:ECF (5-fluorouracil + cisplatin + epirubicin)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
New
Source:
Title:

Upregulation of Autophagy-Related Gene-5 (ATG-5) Is Associated with Chemoresistance in Human Gastric Cancer

Excerpt:
Increased expression of ATG-5 and MPR-1 was significantly correlated with poor overall survival (OS; P<0.01) and disease free survival (DFS; P<0.01) of our GC cohort.
DOI:
https://doi.org/10.1371/journal.pone.0110293