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Association details:
Biomarker:
IDH1 mutation + Chr del(1p) + Chr del(19q)
Cancer:
Oligodendroglioma
Drug:
carmustine
(
DNA synthesis inhibitor
,
Alkylating agent
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
ADULT GLIOMA: OLIGODENDROGLIOMA (IDH-MUTANT, 1p19q CODELETED)….Recurrent or Progressive Disease WHO grade 2, KPS ≥60...Preferred Regimens...Lomustine or carmustine….Other Recommended Regimens...Lomustine or carmustine.
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