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Association details:
Biomarker:
ICAM1 elevation
Cancer:
Solid Tumor
Drug Class:
PD1 inhibitor
+
PD-L1 inhibitor
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
Source:
Clin Transl Sci
Title:
Early changes in soluble intracellular adhesion molecule-1 as prognostic biomarkers to immune checkpoint inhibitor
Published date:
06/14/2023
Excerpt:
Subgroup analysis indicated patients whose sICAM-1 significantly elevated had shorter PFS and OS in both anti-PD-1 and anti-PD-L1 treatment groups.
DOI:
10.1111/cts.13540
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