^
Association details:
| Biomarker: | HPRT1 overexpression |
|---|---|
| Cancer: | Oral Cancer |
| Drug: | cisplatin (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
HPRT1 Promotes Chemoresistance in Oral Squamous Cell Carcinoma via Activating MMP1/PI3K/Akt Signaling Pathway
Published date:
02/09/2022
Excerpt:
We found that highly expressed HPRT1 was associated with a poor prognosis and could promote resistance to cisplatin (CDDP) in OSCC cells in both in vitro and in vivo.
DOI:
10.3390/cancers14040855