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    Association details:
    Biomarker:HOXA11 overexpression
    Cancer:Acute Myelogenous Leukemia
    Drug:cytarabine (DNA synthesis inhibitor, DNA-directed DNAP inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Oncol Rep
    Title:

    HOXA11 plays critical roles in disease progression and response to cytarabine in AML

    Published date:
    06/01/2021
    Excerpt:
    ...finding that chemotherapy responders have higher expression levels of HOXA11. These results indicated that the expression of HOXA11 increased cell apoptosis and predicted an improved response to Ara‑C in AML.
    DOI:
    10.3892/or.2021.8101