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Association details:
| Biomarker: | HMGB1 underexpression |
|---|---|
| Cancer: | Thyroid Gland Carcinoma |
| Drug: | Zelboraf (vemurafenib) (BRAF inhibitor, BRAF V600E inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Involvement of HMGB1 in vemurafenib resistance in thyroid cancer cells harboring BRAF (V600E) mutation by regulating excessive autophagy
Published date:
07/14/2020
Excerpt:
Lower expression of HMGB1 was observed in BRAF-mutant BCPAP cells that had high sensitivity to vemurafenib.
DOI:
10.1007/s12020-020-02417-y
