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Association details:
Biomarker:
HLA-A*11
Cancer:
Solid Tumor
Drug Class:
Immunotherapy
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ESMO 2023
Title:
184P - Patient-specific HLA-I genotypes predict response to immune checkpoint blockade
Published date:
10/16/2023
Excerpt:
In the other cancers subgroup, HLA-A11 and A24 were associated with better OS (HR: 0.20, 95%CI: 0.05-0.85, p= 0.030 and HR: 0.31, 95% CI: 0.10-0.89, p= 0.029, respectively).
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