Both signatures demonstrated a satisfactory predictive accuracy for response: AUC of 0.69 (95% CI: 0.54, 0.84) for the inflammatory and 0.70 (95% CI: 0.55, 0.85) for EMT signatures, respectively....The inflammation signature scores were significantly higher in responders compared to non-responders. (Fig. 1A, +6.0 ± 2.9 vs -5.5 ± 3.4, t-test p = 0.014).