^
Association details:
| Biomarker: | HIF1A underexpression |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Lonsurf (trifluridine/tipiracil) (Thymidine phosphorylase inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Abstract 5266: Continuous trifluridine treatment in colorectal cancer cell lines- investigating its potential
Published date:
05/15/2020
Excerpt:
Additionally, HIF1A related glycolytic mRNA was downregulated in FTD long-treated cell lines compared to that in parental cell lines. Continuous FTD long-term treated cell lines were resistant to FTD.
DOI:
10.1158/1538-7445.AM2020-5266
