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Association details:
| Biomarker: | HHLA2 overexpression |
|---|---|
| Cancer: | Melanoma |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
HHLA2 predicts improved prognosis of anti-PD-1/PD-L1 immunotherapy in patients with melanoma
Published date:
08/08/2022
Excerpt:
Moreover, immunohistochemistry (IHC) analyses of FFPE tissue from melanoma patients revealed that HHLA2 high expression was strongly related to improved response to ICB and indicated a longer progression-free survival (PFS) and overall survival (OS)….Our findings revealed that high expression of HHLA2 has important values in predicting the response to ICB...
DOI:
10.3389/fimmu.2022.902167