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Association details:
Biomarker:HER-2 positive
Cancer:Ovarian Cancer
Drug:EDIT-202 (NK cell stimulant)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

EDIT-202, a Multiplexed CRISPR-Cas12a Gene-Edited iPSC-Derived NK Cell Therapy Has Prolonged Persistence, Promotes High Cytotoxicity, and Enhances In Vivo Tumor Killing

Published date:
05/03/2022
Excerpt:
EDIT-202 induced significantly enhanced anti-tumor efficacy in vivo when evaluated using a SKOV3 HER2+ ovarian cancer model.