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Association details:
Biomarker:
HER-2 negative
Cancer:
HER2 Negative Breast Cancer
Drug:
carboplatin
(
Tubulin polymerization promoter
) +
docetaxel
(
Tubulin polymerization promoter
,
Microtubule stabilizer
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
Source:
NCCN
Title:
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Breast Cancer
Published date:
01/25/2024
Excerpt:
Preoperative/adjuvant therapy regimens, HER2- Negative Regimens...Other Recommended Regimens...Docetaxel + carboplatin (4–6 cycles)
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Source:
clinicaltrials.gov
Title:
Triple Negative Breast Cancer Trial
Excerpt:
......
Trial ID:
NCT00532727
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Source:
clinicaltrials.gov
Title:
Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer
Excerpt:
...- Her-2 negative (IHC 0, 1+ without FISH, or IHC 2+ with...
Trial ID:
NCT05475678
More C2 evidence
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Source:
clinicaltrials.gov
Title:
Neoadjuvant Carboplatin and Docetaxel in Triple Negative Breast Cancer
Excerpt:
...- Breast cancer must be ER-negative, and HER-2 negative according to CAP/ASCO biomarkers testing guidelines....
Trial ID:
CADENCE
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Source:
clinicaltrials.gov
Title:
Neoadjuvant Treatment of Triple Negative Breast Cancer Patients With Docetaxel and Carboplatin to Assess Anti-tumor Activity
Excerpt:
...- HER2 negative by FISH or IHC staining 0 or 1+....
Trial ID:
NCT02124902
^
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