^
Association details:
| Biomarker: | HER-2 L755P |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug: | CL-387785 (EGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Differential Sensitivity of ERBB2 Kinase Domain Mutations towards Lapatinib
Excerpt:
Lapatinib-resistant ERBB2 mutations were found to be highly resistant towards AEE788 treatment but remained sensitive towards the dual irreversible inhibitors CL-387785 and WZ-4002.
DOI:
10.1371/journal.pone.0026760
