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    Association details:
    Biomarker:HER-2 amplification
    Cancer:Gastric Cancer
    Drug:cabazitaxel (Microtubule inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: C3 – Early Trials
    Source:
    Clin Cancer Res
    Title:

    Multicenter Phase II Study of Cabazitaxel in Advanced Gastroesophageal Cancer: Association of HER2 Expression and M2-Like Tumor-Associated Macrophages with Patient Outcome

    Published date:
    07/08/2020
    Excerpt:
    HER2 amplification or overexpression was associated with improved disease control (P = 0.003), PFS (P = 0.04), and overall survival (P = 0.002).
    DOI:
    10.1158/1078-0432.CCR-19-3920