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Association details:
Biomarker:HER-2 amplification
Cancer:Gastric Adenocarcinoma
Drug Class:HER2 inhibitor
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Title:

HER2 copy number as predictor of disease-free survival in HER2-positive resectable gastric adenocarcinoma

Published date:
02/04/2021
Excerpt:
The predictive and prognostic value of HER2 amplification in advanced HER2 inhibitor-treated GA patients has been investigated….Patients with high HER2 CN had a significantly shorter DFS than patients with low HER2 CN (p = 0.002).
DOI:
10.1007/s00432-021-03522-9