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Association details:
Biomarker:
HER-2 amplification
Cancer:
Esophageal Cancer
Drug:
Bavencio (avelumab)
(
PD-L1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C2 – Inclusion Criteria
Source:
clinicaltrials.gov
Title:
Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas
Excerpt:
HER2 amplification confirmed by standard of care testing of tumor specimen (3+ by immunohistochemistry, or 2+ on IHC with ISH with HER2/CEP17 ratio ≥2).
Trial ID:
NCT03783936
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