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Association details:
Biomarker:
HAVCR2 expression
Cancer:
Acute Myelogenous Leukemia
Drug:
Bavencio (avelumab)
(
PD-L1 inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
Source:
ASH 2019
Title:
Single-Cell Mass Cytometry Identifies Mechanisms of Resistance to Immunotherapy in AML
Published date:
11/06/2019
Excerpt:
Expression of PD-L2, OX40, and TIM-3 was detected in the majority of these resistant clones (100%, 86%, and 71%, respectively).
DOI:
10.1182/blood-2019-128601
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