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Association details:
Biomarker:H3.3K27M
Cancer:Glioma
Drug:Focus V (anlotinib) (Multi-tyrosine kinase inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

Targeted therapy with anlotinib for a H3K27M mutation diffuse middle glioma patient with PDGFR-a mutation: a case report

Published date:
11/23/2021
Excerpt:
Anlotinib is a multitarget tyrosine kinase inhibitor, which has not been reported for H3K27M-mt DMG treatment. Here, we firstly reported an adult multifocal H3K27M-mt DMG patient benefiting from anlotinib. This report provides a promising treatment option for H3K27M-mt DMG patients.
DOI:
10.1007/s00701-021-05061-1