^
Association details:
| Biomarker: | H19 overexpression |
|---|---|
| Cancer: | Bladder Cancer |
| Drug: | Keytruda (pembrolizumab) (PD1 inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Distinct gene expression patterns identify patients who relapse after neoadjuvant pembrolizumab and radical cystectomy in the PURE-01 study.
Published date:
02/13/2023
Excerpt:
...we provide a detailed characterization of relapsing pts and identify distinct gene expression patterns with potential utility as novel biomarkers....Differential gene expression analysis identified KRT20 and H19 to be enriched in relapsing patients (both p<0.001).
DOI:
10.1200/JCO.2023.41.6_suppl.549
