This study recruited a total of 186 patients with HGG who were treated with temozolomide plus radiotherapy adjuvant regimen….Patients with GSTP1-H and GSTP1-L were observed in 33 cases and 32 cases, respectively. As exhibited in Figure 5, patients with GSTP1-H showed a trend of worse OS compared with those with GSTP1-L [median OS: 9.2 (95% CI: 3.01–15.39) months vs 16.3 (95% CI: 12.42–20.18) months], although the difference was not statistically significant (χ2=3.247, P=0.072).