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    Association details:
    Biomarker:GSK3B overexpression
    Cancer:Breast Cancer
    Drug:erastin (Ferroptosis inducer)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Mol Cell Biochem
    Title:

    Regulation of GSK3ß/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer

    Published date:
    07/08/2020
    Excerpt:
    We further confirmed that overexpression of GSK-3β strengthened erastin-induced tumor growth inhibition in breast cancer xenograft models in vivo.
    DOI:
    10.1007/s11010-020-03821-8