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Association details:
| Biomarker: | GSK3B overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | erastin (Ferroptosis inducer) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Regulation of GSK3ß/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer
Published date:
07/08/2020
Excerpt:
We further confirmed that overexpression of GSK-3β strengthened erastin-induced tumor growth inhibition in breast cancer xenograft models in vivo.
DOI:
10.1007/s11010-020-03821-8
