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Association details:
| Biomarker: | G6PD deletion |
|---|---|
| Cancer: | Nasopharyngeal Carcinoma |
| Drug: | carboplatin (Tubulin polymerization promoter) + docetaxel (Microtubule inhibitor) + 5-fluorouracil (Thymidylate synthase inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
PO-124 | Nasopharyngeal carcinoma: a therapeutic dilemma for G6PD-deficient patients.
Published date:
02/08/2022
Excerpt:
We present a case of an adult with complete G6PD deficiency, who was treated for NPC at our center….He was scheduled to receive induction chemotherapy with a combination of three cycles of carboplatin (AUC 4), docetaxel (60mg/m2), and 5-fluorouracil (600mg/m2) as a continuous intravenous infusion for 4 days...He demonstrated complete response and he has now been placed on regular follow-up.