^
Association details:
| Biomarker: | FOXO1 underexpression |
|---|---|
| Cancer: | Childhood B Acute Lymphoblastic Leukemia |
| Drug: | cyclophosphamide (Alkylating agent) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Down-Regulated FOXO1 in Refractory/Relapse Childhood B-Cell Acute Lymphoblastic Leukemia
Published date:
11/11/2020
Excerpt:
Lower FOXO1 expression was associated with prednisone and cyclophosphamide resistance...Low FOXO1 transcription was associated with high-risk stratification and relapse in children with B-ALL, probably due to multi-drug resistance.
DOI:
10.3389/fonc.2020.579673
