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Association details:
| Biomarker: | FOLR1 overexpression |
|---|---|
| Cancer: | Ovarian Cancer |
| Drug: | opugotamig olatansine (IMGN-151) (Microtubule inhibitor, Folate receptor 1-targeted antibody-drug conjugate) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Abstract 2890: IMGN151 - A next generation folate receptor alpha targeting antibody drug conjugate active against tumors with low, medium and high receptor expression
Published date:
05/15/2020
Excerpt:
With a novel biparatopic antibody and linker payload design, IMGN151 has shown potent antitumor activity against ovarian cancer models with a broad range of FRα expression…
DOI:
10.1158/1538-7445.AM2020-2890
