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Association details:
Biomarker:
FOLR1 expression
Cancer:
Acute Myelogenous Leukemia
Drug:
ELU001
(
Topoisomerase I inhibitor
,
Folate receptor 1-targeted small molecule-drug conjugate
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
AACR 2022
Title:
1075 / 2 - Therapeutic targeting of CBFA2T3-GLIS2 infant AML with ELU001 - folate receptor alpha-directed C’Dot-drug-conjugate
Published date:
03/09/2022
Excerpt:
...we demonstrated that ELU001 is highly effective at eliminating FOLR1 positive AML cells in vitro and in vivo…
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