An oral squamous cell carcinoma patient harboring a somatic FGFR2 P253R mutation demonstrates a partial response to an FGFR inhibitor….The patient was diagnosed with locally advanced (T2N1M0, stage III) squamous cell carcinoma of the right tongue in 2008 at the age of 52...He began daily treatment with 800 mg pazopanib starting on April 12, 2012. At this time, he had gross disease in the right neck (Figure 5C, left panels). A follow up visit 12 days later showed a marked reduction in tumor size...