^
Association details:
Biomarker:FGFR2 A391E
Cancer:Urothelial Cancer
Drug:fexagratinib (ABSK091) (FGFR inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
New
Title:

Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W

Excerpt:
Patients were treated with AZD4547, 80 mg orally twice daily until progression of disease or drug intolerance....TABLE A3...Clinical Characteristics and Genomic Aberrations of the Patients Who Achieved PR (n = 4) and SD for > 6 months (n = 3)
DOI:
10.1200/JCO.19.02630