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Association details:
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

Futibatinib, an irreversible FGFR1–4 inhibitor, in patients with advanced solid tumors harboring FGF/FGFR aberrations: a phase I dose-expansion study

Published date:
09/22/2021
Excerpt:
Among the 170 patients who received futibatinib 20 mg QD, 10.6% experienced PRs, and 38.2% experienced SD...PRs were observed in a patient with head and neck cancer harboring an FGFR1-PLAG1 fusion (DOR, 5.6 months) and another patient with an FGFR2 p.Y375C mutation (DOR, 10.3 months) whose primary tumor was unknown.
DOI:
10.1158/2159-8290.CD-21-0697
Trial ID: