^
Association details:
| Biomarker: | FGFR1 overexpression |
|---|---|
| Cancer: | Hepatocellular Cancer |
| Drug: | Lenvima (lenvatinib) (c-KIT inhibitor, FGFR inhibitor, VEGFR inhibitor, RET inhibitor, PDGFR α antagonist) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Oxysophocarpine suppresses FGFR1-overexpressed hepatocellular carcinoma growth and sensitizes the therapeutic effect of lenvatinib
Published date:
10/24/2020
Excerpt:
These data collectively provided evidence that FGFR1 overexpression could be a potential cause of lenvatinib resistance...
DOI:
10.1016/j.lfs.2020.118642
