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Association details:
| Biomarker: | FGF4 amplification |
|---|---|
| Cancer: | Hepatocellular Cancer |
| Drug: | sorafenib (Multi-tyrosine kinase inhibitor, pan-RAF inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma†
Excerpt:
FGF3/FGF4 gene amplification is frequently observed in responders to sorafenib in HCC.
DOI:
https://doi.org/10.1002/hep.25956
