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Association details:
| Biomarker: | FGF21 overexpression |
|---|---|
| Cancer: | Hepatocellular Cancer |
| Drug: | Lenvima (lenvatinib) (c-KIT inhibitor, FGFR inhibitor, VEGFR inhibitor, RET inhibitor, PDGFR α antagonist) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Artificial intelligence based on serum biomarkers predicts the efficacy of lenvatinib for unresectable hepatocellular carcinoma
Published date:
12/15/2022
Excerpt:
We retrospectively analyzed patients who had uHCC and received lenvatinib...For OS, increased VEGF, ANG2, FGF19, and FGF21 also showed numerically higher hazard rates, but only FGF21 had a significant association with worse OS (HR, 2.04, P = 0.017).
