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    Association details:
    Biomarker:FGF19 expression
    Cancer:Ovarian Cancer
    Drug:fexagratinib (ABSK091) (FGFR inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    IGCS 2023
    Title:

    THE ANTI-CANCER EFFECTS OF AZD4547 ON OVARIAN CANCER CELLS: DIFFERENTIAL RESPONSES BASED ON FGF19 AND C-MET EXPRESSIONS

    Published date:
    10/18/2023
    Excerpt:
    AZD4547 significantly decreased tumor weight in xenograft models of EOC...We suggest that expression level of c-Met or FGF19 can be a predictive biomarker for AZD4547 treatment...