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Association details:
| Biomarker: | FER overexpression |
|---|---|
| Cancer: | Triple Negative Breast Cancer |
| Drug: | docetaxel (Tubulin polymerization promoter, Microtubule stabilizer) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer
Published date:
04/05/2022
Excerpt:
Strikingly, high-FER MM231 cells displayed a 9-fold higher sensitivity to docetaxel (Figure 2B; half maximal inhibitory concentration [IC50] = 0.63 versus 5.7 nM) and paclitaxel when compared with MM468 cells (Figure S1B; IC50 = 0.93 versus 4.67 nM).
DOI:
10.1016/j.celrep.2022.110584
