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    Association details:
    Biomarker:FBXW7 overexpression
    Cancer:Colon Cancer
    Drug:paclitaxel (Tubulin inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    Ann Transl Med
    Title:

    Attenuating glucose metabolism by Fbxw7 promotes Taxol sensitivity of colon cancer cells through downregulating NADPH oxidase 1 ( Nox1)

    Published date:
    05/17/2021
    Excerpt:
    Overexpression of Fbxw7 sensitized colon cancer cells to Taxol.
    DOI:
    10.21037/atm-21-2076