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Association details:
Biomarker:
FBXW7 overexpression
Cancer:
Colon Cancer
Drug:
paclitaxel
(
Bcl2 inhibitor
,
Tubulin polymerization promoter
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Ann Transl Med
Title:
Attenuating glucose metabolism by Fbxw7 promotes Taxol sensitivity of colon cancer cells through downregulating NADPH oxidase 1 ( Nox1)
Published date:
05/17/2021
Excerpt:
Overexpression of Fbxw7 sensitized colon cancer cells to Taxol.
DOI:
10.21037/atm-21-2076
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