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Association details:
| Biomarker: | FAT1 mutation |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
FAT1 mutations in colorectal cancer patients are associated with the therapeutic benefit of immunotherapy.
Published date:
05/26/2022
Excerpt:
Analysis with survival data from the validation cohort showed that OS was significantly higher in patients with FAT1-mutated tumors than in ones with FAT1 wild-type….Colorectal cancer patients with FAT1 mutations may benefit from immunotherapy.
DOI:
10.1200/JCO.2022.40.16_suppl.e15523
