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    Association details:
    Biomarker:ERCC6 overexpression
    Cancer:Colorectal Cancer
    Drug:5-fluorouracil (Thymidylate synthase inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    New
    Source:
    DNA Cell Biol
    Title:

    Elevated Expression of ERCC6 Confers Resistance to 5-Fluorouracil and Is Associated with Poor Patient Survival in Colorectal Cancer

    Excerpt:
    ...high expression of ERCC6 was associated with poor overall survival in CRC patients with or without receiving 5-FU therapy.
    DOI:
    10.1089/dna.2017.3768