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Association details:
| Biomarker: | ER positive |
|---|---|
| Cancer: | Estrogen Receptor Positive Breast Cancer |
| Drug: | SCR6106 (Selective estrogen receptor degrader) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
1070 - SCR6106, an oral and brain penetrant SERD demonstrated anti-tumor activities in vitro and in vivo
Published date:
03/10/2021
Excerpt:
In addition, SCR6106, showed high activities on ERɑ degradation and anti-proliferation in a panel of ER+ breast cancer cell lines....It showed high potential ability to cross the blood-brain barrier, and could be used to treat HR+ patients with brain metastasis.
