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Association details:
Biomarker:
ER positive
Cancer:
Estrogen Receptor Positive Breast Cancer
Drug:
imlunestrant (LY3484356)
(
Selective estrogen receptor degrader
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
AACR 2021
Title:
1236 - Preclinical characterization of LY3484356, a novel, potent and orally bioavailable selective estrogen receptor degrader (SERD)
Published date:
03/10/2021
Excerpt:
In a panel of breast cancer cell lines, 11 out of 12 ER+ breast cancer cell lines were sensitive to LY3484356...
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