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Association details:
| Biomarker: | EIF4EBP1 overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | tamoxifen (Estrogen receptor antagonist) |
| Direction: | Resistant |
Evidence:
Source:
Title:
High expression of autophagy-related gene EIF4EBP1 could promote tamoxifen resistance and predict poor prognosis in breast cancer
Published date:
07/16/2023
Excerpt:
Decreasing the expression of EIF4EBP1 could reverse TAM resistance, whereas overexpression of EIF4EBP1 promoted TAM resistance….This study indicated that EIF4EBP1 was overexpressed in the BC and TAM-resistant cell line, which increased cell proliferation, invasion, migration and TAM resistance in BC cells.
DOI:
10.12998/wjcc.v11.i20.4788
