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Association details:
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Title:

Chromosomal Copy Number Variation Predicts EGFR-TKI Response and Prognosis for Patients with Non-Small Cell Lung Cancer

Published date:
09/19/2023
Excerpt:
Additionally, independent prognostic significance for OS in EGFR wild-type patients was observed for CNVs in 9q21.31-q22.2 and 11p11.11-q12.1 regions (P = 0.001). Patients with gains in these regions experienced extended OS, while losses were predictive of poorer outcomes.
DOI:
10.2147/PGPM.S418320