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Association details:
Biomarker:EGFR V786M
Cancer:Lung Adenocarcinoma
Drug Class:EGFR inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

A Lung Cancer Patient Harboring a Rare Oncogenic EGFR Exon 20 V786M Mutation Responded to a Third-Generation Tyrosine Kinase Inhibitor: Case Report and Review of the Literature

Published date:
05/18/2022
Excerpt:
A 69-year-old woman was diagnosed with adenocarcinoma cT4N2M1c, stage IVB. Next-generation sequencing (NGS) confirmed a rare EGFR V786M mutation...Subsequent third-generation EGFR TKI showed a remarkable therapeutic effect.
DOI:
https://doi.org/10.3389/fonc.2022.912426