^
Association details:
Biomarker:EGFR V769A
Cancer:Lung Adenocarcinoma
Drug:erlotinib (EGFR inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
New
Source:
Title:

A novel point mutation in exon 20 of EGFR showed sensitivity to erlotinib

Excerpt:
...the patient showed a good clinical response to erlotinib after paclitaxel/cisplatin first-line and docetaxel second-line chemotherapies...Therefore, we suggest that this rare mutation (p.V769A) may be a sensitive EGFR mutation in NSCLC.
DOI:
10.1007/s12032-014-0036-2