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Association details:
Biomarker:EGFR T790M
Cancer:Lung Non-Squamous Non-Small Cell Cancer
Drug Class:PD-L1 inhibitor
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Title:

379 - Effects on immunotherapy of EGFR mutation subtypes in non-squamous NSCLC

Published date:
03/10/2021
Excerpt:
We retrospectively analyzed 510 patients with non-squamous NSCLC treated with anti-PD-(L)1 monotherapy....A significant difference in survival among the four subtypes of EGFR positive group was observed, mutation of T790M only showed a worse PFS and OS probability compared to the other subtypes (p<0.001 and p = 0.002)…