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Association details:
Biomarker:EGFR-RAD51 fusion
Cancer:Non Small Cell Lung Cancer
Drug:gefitinib (EGFR inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

EGFR-RAD51 gene fusion NSCLC responsiveness to different generation EGFR-TKIs: two cases and review of the literature

Published date:
01/14/2022
Excerpt:
Herein, we report the case of two young non smoker females with metastatic NSCLC harboring EGFR-RAD51 gene fusion...The patient, therefore, started first-line treatment with first-generation EGFR-TKI gefitinib...after three months a CT scan showed a complete response (CR)...
DOI:
https://dx.doi.org/10.21037/tlcr-21-888