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Association details:
Biomarker:EGFR-RAD51 fusion
Cancer:Non Small Cell Lung Cancer
Drug:erlotinib (EGFR inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Source:
Title:

Prevalence of EGFR gene fusions in a large cohort of Chinese patients with non-small cell lung cancer (NSCLC).

Published date:
05/16/2018
Excerpt:
The second patient: EGFR-RAD51 fusion driven NSCLC responding to erlotinib will be presented...The patient was considered to have a partial response (PR) to erlotinib.
Evidence Level:
Sensitive: C4 – Case Studies
New
Title:

EGFR-RAD51 fusion variant in lung adenocarcinoma and response to erlotinib: A case report

Excerpt:
Then the patient experienced a remarkable tumor response to erlotinib. Considering this rare EGFR fusion and remarkable response to TKI treatment, we conclude that the incidence of EGFR fusions in NSCLC patients should be attentive.
DOI:
10.1016/j.lungcan.2017.12.001