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Association details:
| Biomarker: | EGFR L858R + EGFR T790M |
|---|---|
| Cancer: | Lung Non-Small Cell Squamous Cancer |
| Drug: | gefitinib (EGFR inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
What management for epidermal growth factor receptor-mutated non-small-cell lung cancer, with squamous cell transformation and T790M-acquired resistance mechanisms? A Case report and review of literature
Published date:
08/03/2021
Excerpt:
We report on tumor progression with SCC histological transformation associated with the T790M mutation in a patient with stage IV bronchial adenocarcinoma with an L858R mutation of the EGFR gene and treated with gefitinib.
DOI:
10.1097/CAD.0000000000001139
