^
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    Association details:
    Biomarker:EGFR H773_V774insH
    Cancer:Non Small Cell Lung Cancer
    Drug:gefitinib (EGFR inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C4 – Case Studies
    New
    Source:
    Sci Transl Med
    Title:

    Structural, biochemical and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer

    Excerpt:
    Response to EGFR TKIs of NSCLCs harboring EGFR exon 20 insertion mutations.
    DOI:
    10.1126/scitranslmed.3007205