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    Association details:
    Biomarker:EGFR G719X
    Cancer:Lung Cancer
    Drug Class:pan-HER inhibitor
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    J Thorac Oncol
    Title:

    Allele-specific role of ERBB2 in the oncogenic function of EGFR L861Q in EGFR-mutant lung cancers

    Published date:
    10/07/2020
    Excerpt:
    ...pan-ERBB inhibitors exerted superior growth inhibitory effects on cells expressing compound L861Q/G719X mutations.
    DOI:
    10.1016/j.jtho.2020.09.019