^
Association details:
Biomarker:EGFR G719X
Cancer:Lung Cancer
Drug Class:pan-HER inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Title:

Allele-specific role of ERBB2 in the oncogenic function of EGFR L861Q in EGFR-mutant lung cancers

Published date:
10/07/2020
Excerpt:
...pan-ERBB inhibitors exerted superior growth inhibitory effects on cells expressing compound L861Q/G719X mutations.
DOI:
10.1016/j.jtho.2020.09.019