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Association details:
| Biomarker: | EGFR G719S |
|---|---|
| Cancer: | Lung Adenocarcinoma |
| Drug: | erlotinib (EGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Activity of Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Patients with Non-small Cell Lung Cancer Harboring Rare Epidermal Growth Factor Receptor Mutations
Excerpt:
The G719S mutation was found in a 50-year-old female never smoker with advanced adenocarcinoma of the lung….she started erlotinib at 150 mg/d. At the first computer tomography scan evaluation, performed 2 months later, disease reduction of multiple primary lung and nodal lesions was evident.
DOI:
10.1097/JTO.0b013e318227e8c6
